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- First-in-Human Evaluation of Anti-von Willebrand Factor Therapeutic Aptamer ARC1779 in Healthy Volunteers.
Gilbert et al. (2007) Circulation, 116, 2678-2686
- Aptamer therapeutics in The Aptamer Handbook,
Cload et al. (S. Klussman ed.), Wiley-VCH (2006)
- Properties of aptamer therapeutics in RNA Medicine,
Medicaldo, Co., Osaka, Japan (2006)
- Co-expression of anti-NFκB RNA aptamers and siRNAs leads to maximal suppression of NFκB activity in mammalian cells
Chan et al. (2006) Nucleic Acids Research, Vol. 34, No. 5
- Pharmacologic and pharmacokinetic assessment of anti-TGFbeta2 Aptamers in rabbit plasma and aqueous humor
McCauley et al. (2006) Pharm Res 23: 303-311
- Direct in vitro selection of a 2'-O-methyl aptamer to VEGF
Burmeister et al. (2005) Chem Biol 12: 25-33
- Conjugation to polyethylene glycol polymer promotes aptamer distribution to healthy and inflamed tissues
Boomer et al. (2005) Oligonucleotides 15:183-95
- Pharmacokinetics and biodistribution of novel aptamer compositions
Healy et al. (2004) Pharm Res 21: 2234-46
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Aptamer Discovery